Thu, 29 Apr 2010
Discovery of Crucial Protein Interaction Sheds Light on Mental Retardation
Prof Edward Manser (PI, NRP) led a team of scientists to be the first to discover a crucial interaction between the protein kinase PAK1, which plays a key role in the formation of synapses in the brain, and the fragile-X-related, or FXR1 protein. This breakthrough, published in the leading journal Molecular Cell on 23 April 2010, sheds light on the molecular mechanisms underlying fragile X syndrome, the most common cause of inherited male mental retardation and a leading genetic determinant of autism, which may lead to a better understanding of the complex causes of this disease.
For more information, please refer to: http://www.a-star.edu.sg/Media/News/PressReleases/tabid/828/articleType/ArticleView/articleId/1247/Default.aspx
Other news relating to this: http://www.sciencedaily.com/releases/2010/04/100422153800.htm
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